HIVHII

Enter a gene symbol into the relevant question input form and the provided information or resource will be shown.

In what cells and tissues is my gene expressed?

Enter gene symbol:

Try an example: STAT3, AKT1

This linked Appyter takes a human gene symbol as the input to produce box plots that display its expression across human cell types and tissue at the mRNA and protein levels.

Under what conditions or perturbations is my gene regulated?

Enter gene symbol:

Try an example: STAT3, AKT1

This linked Appyter generates a volcano plot visualization displaying human/mouse signatures for a gene of interest.

This linked Appyter generates a volcano plot visualization displaying the expression of a specific gene in RNA-seq signatures generated from transformed L1000 data.

What are the transcription factors that regulate my gene?

Enter gene symbol:

Try an example: STAT3, AKT1

Query Enrichr to display transcription factor information from annotated datasets about the input gene symbol.

Is my gene associated with traits in human GWAS?

Enter gene symbol:

Try an example: STAT3, AKT1

Query the GWAS API to find if the input gene symbol is associated with traits from the human GWAS catalog.

Is my gene correlated with other genes?

Enter gene symbol:

Try an example: STAT3, AKT1

Query the ARCHS4 database to return the top 100 correlated genes with the input gene symbol and their pearson correlations.

Is there a knockout mouse for my gene and does it show any phenotypes?

Enter gene symbol:

Try an example: STAT3, AKT1

Query the MGI database through MouseMine to find phenotypes associated with the knockout of the input gene symbol. The produced table also links to the gene page on MGI, the PubMed articles from which they are sourced, and defintions for the returned phenotypes.