GSE87546: Analysis of gene expression in HIV transgenic mice (TG26) with lymphoma in comparison to asymptomatic TG26 mice, and background control (FVBN).Tg26 carries a pNL4-3 HIV-1 provirus lacking part of the gag-pol region, rendering the virus non-infectious.

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Description

Submission Date: Oct 02, 2016

Summary: About 15% of the TG26 mice develop lymphoma. HIV protein expression is observed, particularly the protein p17/Matrix. Total cellular RNA from spleen and lymph nodes from 3 groups of animals: FVB/N controls (n=3), Tg26 asymptomatic (n=6), and Tg26 with lymphoma (n=6). Results provide insights into the gene expression program in animals with lymphoma.

GEO Accession ID: GSE87546

PMID: 27799525

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GROUP CONDITION SAMPLES
Strain + Disease
GSM2333602 GSM2333605 GSM2333608 GSM2333610 GSM2333615 GSM2333616
GSM2333599 GSM2333600 GSM2333601 GSM2333603 GSM2333606 GSM2333611 GSM2333612 GSM2333617 GSM2333618 GSM2333622 GSM2333623 GSM2333624
GSM2333598 GSM2333604 GSM2333607 GSM2333609 GSM2333613 GSM2333614 GSM2333619 GSM2333620 GSM2333621 GSM2333625 GSM2333626 GSM2333627
Description

Submission Date: Oct 02, 2016

Summary: About 15% of the TG26 mice develop lymphoma. HIV protein expression is observed, particularly the protein p17/Matrix. Total cellular RNA from spleen and lymph nodes from 3 groups of animals: FVB/N controls (n=3), Tg26 asymptomatic (n=6), and Tg26 with lymphoma (n=6). Results provide insights into the gene expression program in animals with lymphoma.

GEO Accession ID: GSE87546

PMID: 27799525

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Differential Gene Expression Analysis
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