Submission Date: Jan 06, 2021
Summary: Using specimens from a phase 1b trial of the RV144 regimen in HIV-1-uninfected South Africans (HVTN 097), we profiled innate responses to the first ALVAC-HIV immunization. PBMC transcriptional responses peaked 1 day post-vaccination. Type I and II interferon signaling pathways were activated, as were innate pathways critical for adaptive immune priming.
GEO Accession ID: GSE164366
PMID: 33720973
Select conditions below to toggle them from the plot:
| GROUP | CONDITION | SAMPLES |
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| PBMC |
GSM5008531 GSM5008532 GSM5008533 GSM5008534 GSM5008539 GSM5008540 GSM5008541 GSM5008542 GSM5008599 GSM5008600 GSM5008601 GSM5008602 GSM5008603 GSM5008604 GSM5008605 GSM5008606
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GSM5008507 GSM5008508 GSM5008509 GSM5008510 GSM5008511 GSM5008512 GSM5008513 GSM5008514 GSM5008515 GSM5008516 GSM5008517 GSM5008518 GSM5008527 GSM5008528 GSM5008529 GSM5008530 GSM5008535 GSM5008536 GSM5008537 GSM5008538 GSM5008543 GSM5008544 GSM5008545 GSM5008546 GSM5008547 GSM5008548 GSM5008549 GSM5008550 GSM5008551 GSM5008552 GSM5008553 GSM5008554 GSM5008555 GSM5008556 GSM5008557 GSM5008558 GSM5008559 GSM5008560 GSM5008561 GSM5008562 GSM5008573 GSM5008574 GSM5008575 GSM5008576 GSM5008581 GSM5008582 GSM5008583 GSM5008584 GSM5008585 GSM5008586 GSM5008587 GSM5008588 GSM5008589 GSM5008590 GSM5008591 GSM5008592 GSM5008593 GSM5008594 GSM5008595 GSM5008596 GSM5008597 GSM5008598 GSM5008611 GSM5008612 GSM5008613 GSM5008614
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GSM5008504 GSM5008505 GSM5008506 GSM5008519 GSM5008520 GSM5008521 GSM5008522 GSM5008523 GSM5008524 GSM5008525 GSM5008526 GSM5008563 GSM5008564 GSM5008565 GSM5008566 GSM5008567 GSM5008568 GSM5008569 GSM5008570 GSM5008571 GSM5008572 GSM5008577 GSM5008578 GSM5008579 GSM5008580 GSM5008607 GSM5008608 GSM5008609 GSM5008610
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Submission Date: Jan 06, 2021
Summary: Using specimens from a phase 1b trial of the RV144 regimen in HIV-1-uninfected South Africans (HVTN 097), we profiled innate responses to the first ALVAC-HIV immunization. PBMC transcriptional responses peaked 1 day post-vaccination. Type I and II interferon signaling pathways were activated, as were innate pathways critical for adaptive immune priming.
GEO Accession ID: GSE164366
PMID: 33720973
Select conditions:
Control Condition
Perturbation Condition
This pipeline enables you to analyze and visualize your bulk RNA sequencing datasets with an array of downstream analysis and visualization tools. The pipeline includes: PCA analysis, Clustergrammer interactive heatmap, library size analysis, differential gene expression analysis, enrichment analysis, and L1000 small molecule search.
